immunoSEQ® T-MAP™ COVID

Propel your COVID-19 research

T cells are the adaptive immune system’s first responders to any virus, circulating in the blood to detect and quickly multiply to attack the virus, often before symptoms appear. Adaptive Biotechnologies’ unique MIRA Technology and immunoSEQ Technology have enabled us to create a comprehensive view of the T-cell response to SARS-CoV-2 infection. This data has been made public as part of the ImmuneCODE™ Initiative to help propel drug, vaccine, and clinical trial research.

The immunoSEQ T-MAP COVID offering provides tools for researchers to study the COVID-19 T-cell immune response, including detecting past SARS-CoV-2-specific immune response in research samples & the ability to track responses longitudinally.

Researchers can search our SARS-CoV-2-specific TCR database to determine if their samples show SARS-CoV-2-specific TCRs, the antigens to which these TCR responded, and deeper insights about their samples.
Another feature provides a simple positive or negative result that can help determine past SARS-CoV-2-specific T-cell response in research samples.

SARS-CoV-2-specific antigen-TCR sequence-level data

Quantitative sequence-level data for TCR repertoires for SARS-CoV-2-specific antigens

Past SARS-CoV-2-specific immune response

Detect past SARS-CoV-2-specific immune response in research samples and track responses longitudinally

Dive into patient, population, or cohort-level data

Determine TCR clones shared between cohorts & those that are public vs private clones

Recent publications

Learn more about the science behind the ImmuneCODE database in our first publication and, to discover initial COVID-19 data insights, read our pre-print publication.

Nolan et al.

A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2

VIEW PUBLICATION

Snyder et al.

Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection at Both Individual and Population Levels

VIEW PUBLICATION

KEY FEATURES

End-to-end solution; from experimental design to publication-ready data

SARS-CoV-2-specific TCR repertoire sequences & antigen data

Validated TCR-antigen data from >150 MIRA experiments
Determine past T-cell immune response to SARS-CoV-2 with a simple positive/negative output
In vivo identified SARS-CoV-2-specific TCR sequences
TCR-Antigen sequence-level data with the PCR, bias-controlled, reproducible immunoSEQ Assay

Data analysis through the immunoSEQ Analyzer or computational biology services

Explore SARS-CoV-2-specific TCR-Antigen sequence data in the immunoSEQ Analyzer
Compare your COVID-19 samples against our COVID-19 samples to identify public vs private clones
Computational Biology Services for COVID-19 data and Metadata analysis

Comprehensive COVID-19 TCR-antigen sequence database

Providing you a comprehensive view of SARS-CoV-2-specific antigen and TCR level data
Database will constantly be updated with new findings and TCR-Antigen sequence data

T cells in COVID-19: understanding the immune response to COVID-19

Learn how the immunoSEQ Technology and immunoSEQ T-MAP COVID can be used to better understand the immune response to SARS-CoV-2 infection.

Recent publications

Check out the publications below to learn how researchers are propelling their COVID-19 research by leveraging immunoSEQ T-MAP COVID and the ImmuneCODE COVID-19 database

Sidhom et al.

Analysis of SARS-CoV-2 specific T-cell receptors in ImmuneCode reveals cross-reactivity to immunodominant Influenza M1 epitope

VIEW PUBLICATION

Gittleman et al.

Diagnosis and Tracking of Past SARS-CoV-2 Infection in a Large Study of Vo’, Italy Through T-Cell Receptor Sequencing

VIEW PUBLICATION

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