Discovery Series | Infectious Disease
How well are vaccines holding up against SARS-CoV-2 variants?
As SARS-CoV-2 virus variants emerge, new questions in the worldwide pandemic response are also emerging: What protection do vaccines provide against SARS-CoV-2 variants in terms of infection and disease severity?
In a recent study of the Johnson & Johnson vaccine’s efficacy against variants, researchers used immunoSEQ® T-MAP™ COVID to show that, despite a diminished neutralizing antibody response, vaccine-induced T-cell targeting of SARS-CoV-2 antigens was largely unaffected by mutations in the new variants. The latest evidence on the highly infectious Omicron variant suggests that mutations do not affect 70-80% of previously identified antigen specific T-cell responses to SARS-CoV-2.
COVID-19 Publication Review
In our in-depth COVID-19 publication review, learn more about:
- Detecting the virus and immune response
- Understanding exposure and immunity
- Vaccine and drug development
- Variants and vaccines
- COVID-19’s impact on autoimmune disease
- COVID-19’s impact on oncology
Featured webinar:
Harlan Robins (Adaptive CSO) discusses the T-cell response to COVID-19, vaccination, and variants
The emergence of SARS-CoV-2 variants makes understanding the immune system’s interaction with the virus more crucial than ever because current or future variants have the potential to evade the vaccine-induced immune response. Watch the webinar on COVID-19 vaccine research presented by Harlan Robins, Adaptive’s Chief Scientific Officer, featuring a complete index of the topics and audience discussion.
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Additional Resources
Understanding the T-cell response: SARS-CoV-2 variants and vaccine immune response
View the webinar with Harlan Robins on T-cell responses to SARS-CoV-2 variants and vaccination produced with Nature Research Custom Media.
Immunogenicity of AD26.COV2.S vaccine against sars-cov-2 variants in humans
Learn how T-MAP COVID is being used to assess the impact of variants on vaccine efficacy.
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Effects Of COVID-19 Across Organs And Systems In Healthy And Immunocompromised Individuals
July 2021
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Emerging Themes Around The T-Cell Response & COVID-19: A Look Back At Some Of Our Discussions At World Vaccine Congress 2021
May 2021
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immunoSEQ® T-MAP™ COVID: A Tool To Uncover And Monitor The T-Cell Response in COVID-19
February 2021
View article
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COVID-19 Applications
Learn how immunoSEQ® T-MAP™ COVID can help uncover the T-cell immune response in COVID-19.
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