Our powerful immunosequencing and analysis solution not only delivers a robust and quantitative view of the immune repertoire, but we provide you the flexibility you need to perform your unique experiments by accepting a wide variety of sample types, access to our assays through our Service lab or Kit you can run in your own lab, and dedicated support services to help optimize your experiments and navigate challenges.
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We will send you a customized shipping box along with detailed instructions.
Our expert technicians sequence your DNA samples in our secure, state-of-the-art lab.
Use the immunoSEQ® Analyzer’s powerful, cloud-based analytics toolset to analyze and visualize your data.
Sequence your samples in a lab of your choice, on a schedule that works best for you.
Upload your data to our servers where we check them for quality and normalize them for residual PCR amplification bias.
Use the immunoSEQ® Analyzer’s powerful, cloud-based analytics toolset to analyze and visualize your data.
Species |
Type |
Offering |
Description |
Request Quote |
|---|---|---|---|---|
| Human | TCRB | Service, Kit | Targets the beta chain of the T-cell receptor in the alpha/beta T cells | |
| Human | TCRA/D | Service | Targets the alpha/delta chain of the T-cell receptor | |
| Human | TCRG | Service | Targets the gamma chain of the T-cell receptor | |
| Human | IGH | Service | Targets the heavy chain that forms part of the human B-cell receptor. The immunoSEQ IGH Assay also captures incomplete DJ rearrangements. | |
| Mouse | TCRB | Service | Targets the beta chain of the T-cell receptor in the mouse alpha/beta T cells | |
| Mouse | IGH | Service | Targets the heavy chain that forms part of the mouse B-cell receptor. The immunoSEQ IGH Assay also captures incomplete DJ rearrangements. | |
Use gDNA from archived, fresh or frozen lymphocyte-containing samples:
Sorted T and B cells
Peripheral blood mononuclear cells (PBMCs)
Whole blood
Tissue (fresh, frozen, and formalin-fixed, paraffin-embedded [FFPE] tissue)
Bone Marrow
If you are working with cDNA, contact us and we will help you assess how to best use immunoSEQ® Assays.
When working with genomic DNA (gDNA) or mRNA it is important to understand how sample input can impact measurements used to understand and study the immune repertoire. For archival specimens, gDNA remains more stable compared to mRNA.
With gDNA as starting material, reads can be quantified providing an absolute cell count. This makes it possible to accurately assess clonal expansion and tissue density of T cells. Complementary DNA (cDNA) or mRNA measurements are obscured by cell expression, because mRNA molecules cannot be directly correlated to cell numbers and may not provide an accurate measure of clonality.
When you interrogate gDNA with an unbiased assay, here is what you get:
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Learn how immunoSEQ® T-MAP™ COVID can help uncover the T-cell immune response in COVID-19.
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