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Therapeutic areas

Driving discoveries and propelling research across the world

Our immunosequencing solution has the adaptability to support diverse research applications and needs, including basic immunology, translational research, autoimmune disease, infectious disease, oncology, and much more. Explore how researchers around the world are using the immunoSEQ® Assay to drive discoveries.

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Therapeutic Research Areas
Autoimmune Research
Autoimmune research

Immunosequencing can be used to study and track the health of the immune repertoire in response to self-antigen in multiple disease states by:

  • Monitoring disease dynamics (over time, adverse event, comparing severity, and more)
  • Uncovering disease pathogenesis
  • Evaluate immune response to self-antigens

Watch our recent webinar on the application of immunosequencing in Autoimmune research.

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COVID 19 Research
COVID-19 research

The immunoSEQ® T-MAP™ COVID offering provides tools for researchers to study the T-cell immune response in COVID-19, including:

  • Accessing the underlying technology that powers the first and only T-cell based clinical test for COVID-19 to receive Emergency Use Authorization (EUA)
  • Determining if samples show SARS-CoV-2-specific TCRs and the antigens to which these TCR responded
  • Detecting past T-cell immune response to SARS-CoV-2 with a simple positive or negative result

Watch our recent webinars to learn more about how the immunoSEQ Assay can be applied to COVID-19 research.

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Infectious Disease Research
Infectious disease research

The immunoSEQ Assay can be used to monitor the immune response to pathogens in a variety of disease and treatment states by:

  • Monitoring changes in the T- or B-cell repertoire in response to infection or vaccination
  • Identifying virus-associated clones common to specific pathogens
  • Uncovering disease pathogenesis

See our recent webinars about the application of immunoSEQ Technology in infectious disease research.

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Neurobiology Research
Neurology research

Learn how immunoSEQ can help uncover the role of the adaptive immune system in the central nervous system by:

  • Studying the role of T cells in neurological disorders, neuropsychiatric disorders, & brain metastases.
  • Discovering T-cell-based biomarkers for neurological disorders.
  • Monitoring and characterizing the adaptive immune response to immune-based treatments, vaccines, & therapies

See our recent webinars about the application of immunoSEQ Technology from bench to biomarker in clinical research.

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Oncology Research
Oncology research

Immunosequencing of peripheral blood and/or the tumor microenvironment allows for a comprehensive assessment of an immune repertoire. It also enables identification of an immune response to tumor growth and metastases by characterizing the tumor infiltrating lymphocyte (TIL) population in a sample. Applications include:

  • Identifying predictive and prognostic biomarkers
  • Monitoring responses to therapy/treatment
  • Predicting and monitoring immune related adverse events

See our recent webinars about the application of immunoSEQ Technology in oncology research.

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Transplantation Research
Transplantation research

The immunoSEQ Assay is being applied to both stem cell and solid organ transplantation research to potentially stratify subjects at risk of developing complications, allowing intervention at earlier time points by:

  • Tracking immune reconstitution post stem cell transplant
  • Identifying prognostic biomarkers in liquid transplant and biomarkers of rejection in solid organ transplant
  • Informing dosing of immunosuppressant treatments in solid organ transplant

Watch our latest webinar about applications of the immunoSEQ Technology in the field of transplantation research.

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COVID-19 Applications

Learn how immunoSEQ® T-MAP™ COVID can help uncover the T-cell immune response in COVID-19.

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Resources

Access technical documents for getting started with the immunoSEQ® Service product, grant writing support, and FAQs.

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