Welcome to the SEQing Answers blog. Here we’ll provide tips and guidance for helping researchers use the immunoSEQ platform. Feel free to ask questions using the form in the right column. We'll respond in the next post. Also be sure to sign up for the newsletter so you never miss important information.

Adaptive Biotech Customers at NCI Publish Mouse Study

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Last week, Adaptive customers at the NCI, along with a collaborator at the University of Maryland School of Medicine published results from a study in which they used the immunoSEQ assay to the importance of the expression of ATM (which … Continue reading

Adaptive Clients Publish Latest Results in Journal of Immunology – Now Available Online

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This week, an international team consisting of Adaptive collaborators from Bar Ilan University, the University of Pennsylvania and Rinat-Pfizer published results from a study in which they used the immunoSEQ assay to study DH gene reading frame usage in the … Continue reading

Assays Take Spotlight at Cancer Immunotherapy Meeting

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  Last week, the Cancer Immunotherapy Consortium (CIC) held its annual meeting in Washington, DC, entitled “Entering the Era of Combination Therapies: Practical Implementation.”  The meeting was focused on the complexity of developing combination cancer immunotherapies in light of the … Continue reading

Adaptive Biotechnologies’ Workshop at AAI in Honolulu, HI

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Adaptive Biotechnologies will be giving an Exhibitor Workshop entitled “High-Throughput Sequencing of T cell and B cell Receptors Using immunoSEQ” at the annual American Association of Immunologists (AAI) meeting on Saturday May 4th at 2:00pm in Honolulu, Hawaii. Come learn … Continue reading

Seventh Child to Receive T Cell Leukemia Therapy is Cancer Free

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A 9 year old from Redmond, OR with acute lymphoblastic leukemia is in remission after receiving an experimental modified T cell treatment, according to a post on her father’s Facebook page.  Similar to the results previously published by Stephan Grupp … Continue reading

Will Cancer Diagnostics be the First Application of ‘Precision Medicine’?

In the cancer field we have been at ‘war’ for more than 40 years – ever since the signing of the National Cancer Act in 1971 by President Richard Nixon. Yesterday the NY Times published a great article titled ‘Cancer … Continue reading

Requirements from Experience with Limiting Sample Types

Q: You mentioned working with many different sample types, can you share you experience and requirements for some limiting sample types such as CSF or Synovial fluid? (Sample Preparations) A: We’ve sequenced T and B cells from a wide variety … Continue reading

DNA vs cDNA on the immunoSEQ Assay

One of the recurrent questions that we field is whether our assay is limited to genomic DNA (gDNA), or can also be applied to cDNA.  The answer is a little bit complicated, so please bear with me.  First, to be … Continue reading

Supreme Court To Decide on Whether Genes Can Be Patented

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This week, the Supreme Court is hearing oral arguments in a case, Association for Molecular Pathology v. Myriad Genetics, that will determine the legal validity of patents on genetic testing for BRCA-1 and BRCA-2.  Genotype at these two loci is … Continue reading

A Recap of the AACR Meeting Highlights

At the recent annual meeting of the American Association of Cancer Research (AACR) much attention was paid to new immunotherapeutic approaches to cancer based on harnessing a patient’s immune response to recognize and eliminate malignant cells. The immune system is … Continue reading