immunoSEQ Blog

Newest Updates to the immunoSEQ Analyzer 2.0

We’re at it again! Here are the newest updates that have just been deployed to the analyzer. As always, we’re looking for ways to provide you the best analysis experience. Group Analysis option added for Gene Frequency Histogram Stacked Histogram view added for Gene Frequency Analysis Confidence Intervals added to Sequence Detail Analysis Quality Control… Read More→

Categorized in: Announcements, Software Tips |

Have you signed up to attend the Immunogenomics 2014 conference?

This conference will be held at the HudsonAlpha Biotechnology Campus in Huntsville, Alabama Sept 29 – Oct 1 2014. The deadline for abstract submission is Friday July 18, 2014 at 12pm ET. Harlan Robins (Adaptive Biotechnologies CSO and co-founder) will be the Session Chair at the session entitled ‘Immunodiversity and Individual Responses to Immune Challenge’, which… Read More→

Categorized in: Announcements, Food for Thought |

Diagnosing an Ancient Disease with Shotgun Metagenomics

Italian researchers and their colleagues used DNA sequencing to diagnose an ancient disease observed in a 14th century skeleton excavated from an abandoned settlement in northwest Sardinia.  Kay et al. reported their results in the July 15 edition of mBio, the American Society for Microbiology’s open access journal[i]. On the skeleton, Kay et al. observed… Read More→

Categorized in: Food for Thought |

Baby ‘Cured’ of HIV Now Has Detectable Levels of the Virus in Her Blood

While we all love to share heart-warming stories, this story recently published on CNN health serves as a powerful reminder that miracle cures are rare and don’t come easily.  We live in a complicated world, and everything from viruses to cancer cells, are under selection to evade our detection, escape our treatments and prosper at our… Read More→

Categorized in: Food for Thought |

Building and Using the Adaptive Database of Immune Receptor Sequences

After about 5 years, Adaptive Biotechnologies has now grown to include over 300 academic clients, more than 30 Pharma clients, and a CLIA-approved clinical service that serves a number of major tertiary care medical centers. The immunoSEQ platform has now generated over 65 billion total sequences of which greater than 1.24 billion are unique (representing independent V(D)J… Read More→

Categorized in: Food for Thought |

B Cells: More than just a pretty antibody

In an article published online with the Journal of Immunology 1 July, 2014, investigators led by Dr. Shane Grey from the Garvan Institute of Medical Research in Sydney, NSW, Australia, report on a novel function of B cells in adaptive immune system development and function.  The authors specifically report on their identification of a role in… Read More→

Categorized in: Food for Thought |

Veteran Microsoft Executive and Distinguished Engineer, Sean Nolan, joins Adaptive Biotechnologies as Chief Technology Officer

SEATTLE, June 17, 2014 (PR NEWSWIRE) – Adaptive Biotechnologies, a clinical stage diagnostics company that leverages Next Generation Sequencing (NGS) to profile the adaptive immune system, is pleased to announce the appointment of Sean Nolan as Chief Technology Officer and the newest member of the Company’s expanding Executive Leadership Team. Mr. Nolan’s hire, the second… Read More→

Categorized in: Announcements, Press Release |

Clinical Immunology on PLOS

The nonprofit open access scientific publishing project, PLOS (Public Library of Science), now has a Clinical Immunology collection. The collection initially contains sections for “Allergies & Anaphylaxis” and “Tumor Immunology”, which have been seeded with previously published PLOS content, and more sections will be added over the coming months. The full announcement can be read here. 

Categorized in: Food for Thought |

Adaptive Customers Publish Latest Results in Science Translational Medicine

Screen Shot 2013-12-04 at 12.30.01 PM

A few months ago, a team of researchers from Memorial Sloan-Kettering Cancer Center, New York-Presybyterian, Wiell Cornell and Columbia published results from a study in which they used the immunoSEQ assay to evaluate a specific therapy on 16 patients with B cell Acute Lymphoblastic Leukemia. The study resulted in the findings that the therapy was as effective in high-risk… Read More→

Categorized in: Announcements |

New Insights into T-cell Receptor Cross-Reactivity

T-cell receptors (TCRs) recognize peptides displayed by major histocompatibility complex (MHC) molecules on the surface of cells. While the immune system contains a diverse repertoire of T-cell receptors to allow for the recognition of many different antigens, each individual T-cell receptor may also be able to bind to several different peptides, a phenomenon known as… Read More→

Categorized in: Food for Thought |