immunoSEQ Blog

Adaptive Announces Acquisition of Sequenta, Inc.

ADAPTIVE ANNOUNCES ACQUISITION OF SEQUENTA, INC.  Deal Expected to Expedite the Development and Commercialization of Immunosequencing Applications SEATTLE, WA, Jan 7, 2015 — Adaptive Biotechnologies Corporation, a pioneer in leveraging next generation sequencing to profile T-cell and B-cell receptors, today announced the acquisition of Sequenta, Inc. which is expected to expedite and expand the use of novel… Read More→

immunoSEQ Customers Publish Latest Results in the Journal of Biological Chemistry

Last week, a team of researchers from Case Western Reserve University School of Medicine published results from a study in which they used the immunoSEQ assay to profile the CD4+ T cell repertoire after stimulation with certain polysaccharides. The study resulted in the findings that MHCII-presented polysaccharides are specifically recognized by CD4+ T cells with regulatory T cell… Read More→

Categorized in: Announcements |

immunoSEQ Customers Publish Latest Results in Leukemia Research Reports

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A couple weeks ago, a team of researchers from York Hospital and University of Virginia Cancer Center published results from a study in which they used the immunoSEQ assay to profile the T cell repertoire of a patient with T-LGL leukemia. The study resulted in findings suggesting that T and NK-LGL leukemia may share common pathogenesis mechanisms and… Read More→

Categorized in: Announcements |

immunoSEQ Customers Publish Latest Results in Annuals of the Rheumatic Diseases

A couple weeks ago, a team of researchers from Sanford-Burnham Medical Research Institute, Singhealth and Duke-NUS Graduate Medical School, Seattle Children’s Hospital and Research Institute, Fondazione IRCCS Policlinico San Matteo, IRCCS Ospedale Pediatrico Bambino Gesu, University Genoa and G Gaslini Institute and Cincinnati Children’s Hospital Medical Center published results from a study in which they used… Read More→

Categorized in: Announcements |

immunoSEQ Customers Publish Latest Results in ScienceXpress

Earlier this month, a team of researchers from Università della Svizzera Italiana, ETH Zurich, and Netherlands Cancer Institute published results from a study in which they used the immunoSEQ assay to look at the degree of interclonal and intraclonal functional heterogeneity of the human CD4+ T cell response post-antigenic stimulation. The study resulted in the findings that… Read More→

Categorized in: Announcements |

immunoSEQ Customers Publish Latest Results in Genes & Development

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In late October, a team of researchers from Rutgers Cancer Institute of New Kersey, Rutgers Robert Wood Johnson Medical School, Adaptive Biotechnologies, Fred Hutchinson Cancer Center, and Institute for Advanced Study published results from a study in which they used the immunoSEQ assay to profile T cells in a thymic lymphoma p53 knockout mouse model. The… Read More→

Categorized in: Announcements |

immunoSEQ Customers Publish Latest Results in Molecular Immunology

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This past month, a team of researchers from University of Turku and University of Helsinki published results from a study in which they used the immunoSEQ assay to investigate if T cell accumulation in islets during early insulitis is clonally predetermined by comparing the CDR3 sequences present in islet-infiltrating T cells in young pre-diabetic NOD mice…. Read More→

Categorized in: Announcements |

Recent GenomeWeb Article Discusses Immunosequencing Advances And Clinical Utility

An article written this past week by Monica Heger of GenomeWeb discussed how immunosequencing is advancing closer towards clinical utility.  Adaptive Biotechnology is featured prominently in the article, along with several other companies known in the space.  Example studies from the article include those well known to Adaptive; clone tracking over time for Minimal Residual… Read More→

Categorized in: Food for Thought |

Seattle Children’s Researchers Report Promising Results in ALL Trial

Our colleagues at the Ben Towne Center for Childhood Cancer Research from Seattle Children’s recently reported extremely promising preliminary results in their ongoing clinical trial for relapsed acute lymphoblastic leukemia (ALL) in children and young adults. Dr. Rebecca Gardner’s presentation at the Annual Meeting of the American Society of Hematology last week revealed that 12 of… Read More→

Categorized in: Announcements, Food for Thought |

Contaminomics

Let’s take a look at a recent highly accessed publication in BMC Biology about contamination during next-generation DNA sequencing leading to the making of incorrect conclusions in a study. The title of the paper is: “Reagent and laboratory contamination can critically impact sequence-based microbiome analyses” and the manuscript can be accessed here. Let us also provide… Read More→

Categorized in: Food for Thought |