immunoSEQ Blog

Combining Immunotherapies

In December, Nature Publishing Group launched an open access journal called Molecular Therapy – Oncolytics which will focus on the development of biological therapies targeting cancer. Topics will include advancements in therapies such as adoptive T-cells and oncolytic viruses (OVs). One of the initial articles published was a review by Jedd Wolchok and Dmitriy Zamarin making the… Read More→

Categorized in: Food for Thought |

Adaptive and Adaptive Customers Publish Latest Results in Journal of Virology

A couple weeks ago, a team of researchers from Adaptive Biotechnologies, University of Washington, and the Fred Hutchinson Cancer Research Center published results from a study in which they used the immunoSEQ assay to report the identity of activated effector T cell clones that expand in response to the yellow fever vaccine two weeks post-vaccination (as… Read More→

Categorized in: Announcements |

Adaptive Customers Publish Latest Results in Molecular Immunology

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Last month, a team of researchers from Charles University Prague, University Hospital Motol and General University Hospital in Prague published results from a study in which they used the immunoSEQ assay to profile T and B cell populations in children with Periodic Fever, Aphtous Stomatitis, Pharyngitis, and Adenines (PFAPA) syndrome. The results suggested that the uninhibited, polyclonal response… Read More→

Categorized in: Announcements |

Adaptive Customers Publish Latest Results in Science Translational Medicine

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Last week, a team of researchers from Columbia University Medical Center, Fred Hutchinson Cancer Research Center, and Massachusetts General Hospital published results from a study in which they used the immunoSEQ assay to examine the TCRB repertoire of patients who underwent a combined kidney and bone marrow transplantation.  The results showed a set of patient-specific T cell… Read More→

Categorized in: Announcements |

Adaptive Customers Publish Latest Results in Clinical Immunology

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At the beginning of the month, a team of researchers from Montefiore Medical Center, Adaptive Biotechnologies, and Icahn School of Medicine at Mount Sinai recently published results from a study in which they used the immunoSEQ assay to examine the structure and composition of the T cell receptor β chain in Common Variable Immune Deficiency (CVID).  Common Variable… Read More→

Categorized in: Announcements |

Adaptive Customers Publish Latest Results in Transplantation

A team of researchers from Northwestern Memorial Hospital, University of Louisville, and Regenerex recently published results from a study in which they used the immunoSEQ assay to monitor immune reconstitution in patients receiving kidney plus hematopoietic stem cell transplants.  Our assay was able to distinguish the donor immune system from the recipient’s immune system. The abstract is reprinted… Read More→

Categorized in: Announcements |

Adaptive Announces Acquisition of Sequenta, Inc.

ADAPTIVE ANNOUNCES ACQUISITION OF SEQUENTA, INC.  Deal Expected to Expedite the Development and Commercialization of Immunosequencing Applications SEATTLE, WA, Jan 7, 2015 — Adaptive Biotechnologies Corporation, a pioneer in leveraging next generation sequencing to profile T-cell and B-cell receptors, today announced the acquisition of Sequenta, Inc. which is expected to expedite and expand the use of novel… Read More→

immunoSEQ Customers Publish Latest Results in the Journal of Biological Chemistry

Last week, a team of researchers from Case Western Reserve University School of Medicine published results from a study in which they used the immunoSEQ assay to profile the CD4+ T cell repertoire after stimulation with certain polysaccharides. The study resulted in the findings that MHCII-presented polysaccharides are specifically recognized by CD4+ T cells with regulatory T cell… Read More→

Categorized in: Announcements |

immunoSEQ Customers Publish Latest Results in Leukemia Research Reports

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A couple weeks ago, a team of researchers from York Hospital and University of Virginia Cancer Center published results from a study in which they used the immunoSEQ assay to profile the T cell repertoire of a patient with T-LGL leukemia. The study resulted in findings suggesting that T and NK-LGL leukemia may share common pathogenesis mechanisms and… Read More→

Categorized in: Announcements |

immunoSEQ Customers Publish Latest Results in Annuals of the Rheumatic Diseases

A couple weeks ago, a team of researchers from Sanford-Burnham Medical Research Institute, Singhealth and Duke-NUS Graduate Medical School, Seattle Children’s Hospital and Research Institute, Fondazione IRCCS Policlinico San Matteo, IRCCS Ospedale Pediatrico Bambino Gesu, University Genoa and G Gaslini Institute and Cincinnati Children’s Hospital Medical Center published results from a study in which they used… Read More→

Categorized in: Announcements |