immunoSEQ Blog

Seattle Children’s Researchers Report Promising Results in ALL Trial

Our colleagues at the Ben Towne Center for Childhood Cancer Research from Seattle Children’s recently reported extremely promising preliminary results in their ongoing clinical trial for relapsed acute lymphoblastic leukemia (ALL) in children and young adults. Dr. Rebecca Gardner’s presentation at the Annual Meeting of the American Society of Hematology last week revealed that 12 of… Read More→

Categorized in: Announcements, Food for Thought |

Contaminomics

Let’s take a look at a recent highly accessed publication in BMC Biology about contamination during next-generation DNA sequencing leading to the making of incorrect conclusions in a study. The title of the paper is: “Reagent and laboratory contamination can critically impact sequence-based microbiome analyses” and the manuscript can be accessed here. Let us also provide… Read More→

Categorized in: Food for Thought |

Meet Our New Field Team

FAS team

Hopefully you’ve heard the exciting news about the launch of our immunoSEQ™ hsTCRB Kit (For Research Use Only), but that’s not all of the new and exciting news we have to share. We now have a dynamite team of field-based specialists to support our immunoSEQ™ Platform! Over the last six months Adaptive has been growing… Read More→

Categorized in: Announcements |

Reproducible Results Using the immunoSEQ hsTCRB Kit

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The launch of the immunoSEQ human T cell receptor beta (hsTRCB) Kit allows researchers to assay TCRB repertoires in their own lab(s) using the same breath-through technology Adaptive Biotechnologies offers through its immunoSEQ Service. The ability to examine T-cell repertoires down to the individual T-cell level is incredibly powerful and is being applied in a… Read More→

Categorized in: Announcements, Food for Thought |

GSK Reports Promising Results with their Latest Ebola Vaccine Safety Trial

Ebola has been getting a lot of attention in the past several months, and GSK has just reported via the New England Journal of Biomedicine that they have found very promising results with their latest vaccine safety trial. In a trial of 20 healthy people, they found the vaccine to produce an encouraging immunogenic response… Read More→

Categorized in: Food for Thought |

Towards clinical applications of adoptive TIL transfer

The immunoSEQ BLOG is replete with examples of Adaptive Biotechnologies’ customers’ application of adoptive T-cell transfer (ACT) as a therapy for diverse cancer types.  A recent publication from the Department of Oncology and Pathology at the Karolinska Institute Cancer Center in Stockholm, Sweden, documents a study combining the adoptive transfer of tumor-infiltrating lymphocytes (TILs) with… Read More→

Categorized in: Food for Thought |

Adaptive Customers Publish Latest Results in Nature

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Last week, a team of researchers from UCLA, Jonsson Comprehensive Cancer Center, Merck, Gustave Roussy and INSERM, Adaptive Biotechnologies, and Fred Hutchinson published results from a study in which they used the immunoSEQ assay to confirm presence of active immune response in responders prior to treatment.  The study resulted in the findings that the assay as able to help… Read More→

Categorized in: Announcements |

Adaptive Customers Publish Latest Results in Cancer Immunology, Immunotherapy

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Recently, a team of researchers from Karolinska Institutet published results from a study in which they used the immunoSEQ assay to explore the repertoire of patients with state 4 melanoma with combined TIL infusion and dendritic cell vaccination.  The study resulted in the findings that there was a presence of highly dominant clones in most  infusion products, and… Read More→

Categorized in: Announcements |

Cloud vs. Local IT infrastructure in Biotech

Our Director of IT often faces decisions on where to provide the IT infrastructure. Do we build it internally or do we leverage the cloud? Our business here at Adaptive grows at the speed of light and we often can’t scale our internal IT systems at the pace the business needs. Thankfully the cloud is maturing… Read More→

Categorized in: Food for Thought |