immunoSEQ Blog

Cloud vs. Local IT infrastructure in Biotech

Our Director of IT often faces decisions on where to provide the IT infrastructure. Do we build it internally or do we leverage the cloud? Our business here at Adaptive grows at the speed of light and we often can’t scale our internal IT systems at the pace the business needs. Thankfully the cloud is maturing… Read More→

Categorized in: Food for Thought |

Insights into how antibody therapies might block Ebola


Researchers at the Scripps Research Institute published data this week characterizing how the monoclonal antibody therapy ZMapp recognizes the Ebola virus. ZMapp is actually a mixture of three chimeric antibodies. Erica Ollmann Saphire, Andrew Ward, and colleagues reported single particle electron microscopy images showing how each of these three antibodies binds to the glycoprotein on the… Read More→

Categorized in: Food for Thought |

Adaptive Customers Publish Latest Results in Cell

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Last week, a team of researchers from Columbia University Medical Center, Columbia University, and the New York Organ Donor Network published results from a study in which they used the immunoSEQ assay to provide a multidimensional, quantitative analysis of human T cell compartmentalization and maintenance over 6 decades of life in blood, lymphoid, and mucosal tissues… Read More→

Categorized in: Announcements |

International Trial Examines if Viral Reservoirs Can Be Eliminated in HIV Infected Infants

Last Monday, the NIH announced a global Phase I/II proof-of-concept clinical trial to study the effects of giving HIV infected newborns antiretroviral treatment within 2 days of birth. Medication will continue until 2 years of age, and the children will stay off of it as long as the virus can’t be detected. The story can… Read More→

Categorized in: Food for Thought |

New Adaptive Publication with Client Collaborators from Northwestern University

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Last week, a team of researchers from Adaptive Biotech, Northwestern University, and the Fred Hutchinson Cancer Research Center published results from a study in which they used the immunoSEQ assay to help define the alloreative T cell repertoire of mixed lymphocyte reaction cultures.  The study resulted in the discovery that thousands of T cell clones… Read More→

Categorized in: Announcements |

Using carrier cells or carrier DNA in preparing samples with limited numbers of T cells

Q: We are preparing to perform sequencing of TCRs from limited numbers of T cells. For one of our projects, we would like to perform TCR sequencing on patient tissue biopsy or blister fluid samples having T cell infiltrates with potential oligoclonal T cell expansions. Unfortunately, these patient samples will have limited numbers of T cells,… Read More→

Categorized in: Questions & Answers |

Adaptive Customers Dress Up For Halloween Too!

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Here at Adaptive, we had loads of fun dressing up for Halloween last week. Apparently our customers had fun dressing up as well! Here’s one of our customers from the Kupper lab at Brigham & Women’s Hospital dressing up as our Adaptive water bottle that goes out with every box we ship. Great  costume Lizzy!… Read More→

Categorized in: Just for Fun |

The Ebola Vaccine Race Contestants

There is constant news about an Ebola vaccine race in the popular press.  What are these vaccines? The three frontrunners are all using viruses to carry genetic material that makes Ebola proteins into patients so that patients can generate an immune response.   GlaxoSmithKline and NewLink Genetics are currently doing Phase I testing, with Johnson &… Read More→

Categorized in: Food for Thought |