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Introducing… immunoSEQ 2.0′s new tagging feature!
At Adaptive, we’re always trying to make the analyzer tools faster and easier to use. In just a few months, we will be introducing a completely redesigned search and associate samples experience that does just that. The new tagging feature … Continue reading
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Staring at the Repertoire, Searching for Satellites
One thing we’re occasionally asked is how to survey a sample data set for satellite cancer clones. In practice, it’s not a trivial matter to identify every cancer clone. It’s likely that the majority of satellite clones are not difficult … Continue reading
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Comparing Samples of Normalized Copy Numbers
Q: How can we compare two samples of normalized copy numbers? When we use the log scatter pattern, unnormalized copy number automatically shows up. A: Our current version of the online tool immunoSEQ has a default setting of unnormalized. The … Continue reading
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Creating a 3D Histogram in Excel from Raw Sequence Data
Q: I have my raw sequence data and want to use excel to create a 3D histogram. How is this done? A: Use the following steps… Go to sample files>check all and download to desktop Unzip file>open .txt in Excel … Continue reading
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immunoSEQ Analysis Suite Compatibility & Troubleshooting Tips
As part of our service, we offer access to our immunoSEQ analysis suite that provides the tools needed to view and analyze the immune repertoire data, also allowing simultaneous analysis of multiple samples in your project . The analysis suite includes … Continue reading
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Exciting new developments coming in immunoSEQ 2.0!
Our software engineers are hard at work developing the newest release of our immunoSEQ Analyzer. Below, you can see a sneak peak of one of the cool features that will be available to you upon it’s release. As it stands … Continue reading
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Plotting CDR3 lengths by each vB family for individual specimens
Q: Is there a way to plot CDR3 lengths by each vB family for individual specimens? A: I would take each .tsv file, highlight the columns from V family to CD3 lengths and export as a pivot table. You can … Continue reading
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Now Available in the immunoSEQ Analyzer- Scatterplots by Frequency & Comparing 2 Samples with Tie Information
ImmunoSEQ has a couple of new analysis options: you can now look at scatterplots by frequency (percentages) and can compare two samples with tie information. The scatterplot by frequency option converts the sequence counts into percentages relative to the total … Continue reading
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Script to consolidate clone counts per unique amino acid string in the samples summary tsv file
The tsv files that are downloaded from ImmunoSeq contain the count and frequency of each nucleotide clone identified. Sometimes multiple lines of this file may contain the same CDR3 amino acid sequence when 1) receptors having difference nucleotides translate to … Continue reading
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Overview of immunoSEQ Analysis Tools & Capabilities
Our immunoSEQ tools have been evolving over a period of time and have gone through several changes. They have also adopted new capabilities in adding value to immunoSEQ’s TCR & BCR repertoire data. A quick overview of the different options … Continue reading
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